Monday, 01. December 2008

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PROJECTS  (88) PUBLICATIONS  (156) MEMBERS  (57) INSTITUTIONS  (1)

Competence platform


This website is only filled with sample research information and serves primarily to illustrate the concept of the Competence platform. All partners to the BioCompetence Network have access to the Competence platform at www.bio-competence.com (password protected), where their research competences are thematically accessible and possible to analyse through novel tools.

If you desire more information, please contact the PR Office of the BioCompetence Network at info@biocompetence.org.




88 Projects relatiert zu Competence platform
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1 / 9
Modulation of Proteolysis in Tumor Cells (Maria G. Masucci)

Using a panel of LCLs EBV carrying BL lines and pairs of BL/LCL-like cells of the same genetic background we have found that BL cells are resistant to the induction of apoptosis and fail to accumulate » more
Bacterial recognition by epithelial cells (Agneta Richter-Dahlfors)

Upon recognition of conserved molecular microbial patterns (e.g. LPS and cell wall components) Toll-like ... » more
Pseudomonas aeruginosa: Large chromosomal inversions (Ute Römling)

Large chromosomal inversions occur in the genomes of all species, but become commonly not fixed in the chromosome. However, the chromosomes of closely related species or subspecies can be usually » more
Bacterial virulence factors and relations to the host response (Roland Möllby)

The group investigates occurrence of bacterial virulence factors and relations between them and the host response. We investigate Escherichia coli urinary tract infections and their immune response » more
Has the number of tumor antagonizing genes been underestimated? (Georg Klein)

Ever since the early 50s, my and my collaborators? research work has resolved around multistep carcinogenesis. In the early 50s, we have been among the first to document the role of Darwinian » more
Mechanisms of apoptosis regulation in B-chronic lymphocytic leukemia (Mikael Jondal)

B-cell chronic lymphocytic leukemia (B-CLL) is the most common adult B-cell malignancy in the Western world and is characterized by the accumulation of monoclonal CD5+ B cells. The clinical course of » more
Reactivation of p53 by small molecules: a novel strategy to combat cancer (Galina Selivanova)

The vast majority of tumors have acquired defects in p53 as an essential step in tumorigenesis. 50% of tumors overexpress p53 which is nonfunctional due to unfolding caused by missence point mutation, » more
Biobanking (Ingemar Ernberg)

In collaboration with Department for Medical Epidemiology (MEP) we are preparing a biobank on blood samples from 1000 lymphoma patients and 2000 controls, as part of large molecular epidemiologic » more
Helicobacter vaccine (Lars Engstrand)

We have initiated a collaboration with an Austrian vaccine development company with the aim of developing a vaccine against H. pylori. Using a novel and innovative, genomic-based method, we are in the » more
MHC: Petide: TCR Interaction (Victor Levitsky)

At least eight viral proteins expressed in the latently infected immunoblasts provide the targets for EBV specific CTL responses. In a number of cases, reconstitution experiments with synthetic » more
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